When the body of a young girl who was killed over 40 years ago is discovered at the bottom of Lake Mead, Max Roby promises her mother, Raquel Williams, that the CSI team will finally find justice for her daughter.
The CSI team probes an antique shop owner's gunshot death lacking a crucial clue - the bullet. Meanwhile, Max gains ground in the ongoing robotics factory case involving Ocho.
When David Hodges goes missing, the CSI team searches for any piece of evidence that can help locate him, clear his name, and save the reputation of the lab.
The CSI team investigates when a nervous system is found hanging above a local car dealership. Also, Chavez and Max search for a missing source in their ongoing investigation of the robotics factory.
The CSI team investigates the eccentric world of sideshows when a couple of performers are discovered burnt in a pit. Hodges mulls a plea deal as as his criminal trial kicks off.
After an explosion in a bio lab, the CSI team races to determine which nerve agent left one of their own unconscious, while the others explore a dangerous underground tunnel to find another CSI who got kidnapped during the blast.
When a young, non-verbal boy is found hiding in a stranger's garage, the CSI team searches for his missing mother. Also, Max receives a strange letter with symbols in silver ink that Folsom and Allie recognize from prior crime scenes.
As the CSI team investigates the death of a man visiting Las Vegas for a health and wellness convention, a fiery explosion traps Allie Rajan in the basement of an abandoned hospital.
When a fitness guru is found dead in a gym sauna and his soon to be son-in-law is found dead from an apparent hunting accident, the CSI team investigates to see if these deaths are unrelated tragic accidents or if they're connected.